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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Isoform D of Beta-secretase 1 (BACE-I-432)
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM207627
(US9260455, 6)
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Affinity Data
IC50: 718nM
pH: 4.5 T: 2°C
Assay Description:
A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM207627
(US9260455, 6)
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Copy InChI
Affinity Data
IC50: 5.08E+3nM
pH: 4.5 T: 2°C
Assay Description:
This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI