Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM384288(Trans-2-(((2′-fluoro-5′-isopropoxy-[1,...)
BDBM384291((METHOD A) | US9938222, Example 2)EC50: 250nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
BDBM384301((1R,2S)-2-(((2′-Fluoro-5′-isopropoxy-[...)EC50: 1.69E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
BDBM384301((1R,2S)-2-(((2′-Fluoro-5′-isopropoxy-[...)
EC50: 2.81E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
BDBM384302((1S,2R)-2-(((2′-Fluoro-5′-isopropoxy-[...)EC50: 2.86E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
BDBM384292((METHOD A) | US9938222, Example 3)EC50: 470nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair