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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 14 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  316nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1125 residues) expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues) expressed in baculovirus infected insect cells using RHK-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 11(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of human recombinant N-terminal Streptavidin2-tagged HDAC11 (1 to 347 residues) expressed in baculovirus infected insect cells using Boc-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 8(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  3.41E+3nMAssay Description:Inhibition of recombinant C-terminal His-fusion tagged and N-terminal Streptavidin2-tagged human HDAC8 (1 to 377 residues) expressed in insect cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  4.91E+3nMAssay Description:Inhibition of recombinant human GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected sf21 cells using RHK-K(Ac)-AMC as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 5(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  5.51E+3nMAssay Description:Inhibition of recombinant human C-terminal His-fusion tagged HDAC5 (657 to 1123 residues) expressed in baculovirus infected insect cells using Boc-K(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  6.06E+3nMAssay Description:Inhibition of recombinant full length human FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using RHK-K(Ac)-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC7 (518 to 991 residues) expressed in baculovirus infected insect cells using Boc-K(Ac)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged SIRT1 (1 to 747 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 4(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged and C-terminal His-tagged human HDAC4 expressed in baculovirus infected insect cells using RHK-K(Ac)-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HDAC10 using fluorescent-labelled p53 residues 379 to 382 (RHKKAc) peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HDAC9 using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  7.72E+4nMAssay Description:Inhibition of FITC-geldanamycin binding to recombinant human full-length C-terminal His-tagged HSP90alpha expressed in Escherichia coli after 3 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50519398(CHEMBL4448385)
Affinity DataIC50:  3.61E+5nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed