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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
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Affinity Data
Ki: 7.10E+4nM
Assay Description:
Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Histone acetyltransferase GCN5
(Saccharomyces cerevisiae S288c)
Mayo Clinic
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
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Affinity Data
IC50: 1.40E+3nM
Assay Description:
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90E+3nM
Assay Description:
Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction expressed in Escherichia coli BL21 codon plus cells using FITC-beta-DEETGEF-OH ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone acetyltransferase GCN5
(Saccharomyces cerevisiae S288c)
Mayo Clinic
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.10E+3nM
Assay Description:
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of FAM-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measur...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of FAM-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measur...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
Kd: >5.00E+5nM
Assay Description:
Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.90E+3nM
Assay Description:
Binding affinity to human KEAP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.90E+3nM
Assay Description:
Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction assessed as equilibrium dissociation constant using FITC-betaAla-DEETGEF-OH as ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Nuclear factor erythroid 2-related factor 2
(Homo sapiens (Human))
University College London
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
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Affinity Data
EC50: 2.90E+3nM
Assay Description:
Inhibition of Keap1 (unknown origin) interaction to Nrf2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.60E+3nM
Assay Description:
Binding affinity to human KEAP1 by fluorescence anisotropy assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Nuclear factor erythroid 2-related factor 2
(Homo sapiens (Human))
University College London
Curated by
ChEMBL
Ligand
BDBM50076479
(CHEMBL3235901)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.90E+3nM
Assay Description:
Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as compound's equilibrium dissociation constant after 60 mins by fluorescence anisotro...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI