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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50588691(CHEMBL5170634)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50588691(CHEMBL5170634)
Affinity DataIC50:  4.48E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged HDAC2 (1 to 488 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50588691(CHEMBL5170634)
Affinity DataIC50:  8.01E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50588691(CHEMBL5170634)
Affinity DataIC50:  8.35E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50588691(CHEMBL5170634)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 insect...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50588691(CHEMBL5170634)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In DepthDetails PubMed