Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380625(6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5-(3,...)
BDBM380625(6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5-(3,...)
IC50: 25nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380661((R)-6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5...)
IC50: 27nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380661((R)-6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5...)
IC50: 33nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380625(6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5-(3,...)
IC50: 41nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380661((R)-6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5...)
IC50: 41nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380661((R)-6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5...)
BDBM380625(6-(4-chlorophenyl)-2-(2,5-dihydrofuran-3-yl)-5-(3,...)
IC50: 5.70E+3nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair