Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM380781((6R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tri...)
BDBM380781((6R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tri...)
IC50: 12nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380780(6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]triazolo...)
IC50: 31nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380780(6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]triazolo...)
IC50: 43nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380781((6R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tri...)
BDBM380780(6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]triazolo...)
IC50: >3.70E+4nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair