Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380694((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
BDBM380694((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
IC50: <11nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380694((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
IC50: <11nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380692(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-5...)
IC50: 21.5nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380692(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-5...)
IC50: 26nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380692(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-5...)
IC50: 46nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380694((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
BDBM380692(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-5...)
IC50: 3.40E+3nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair