Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM380782((6R)-6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d...)
BDBM380712(6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2...)
IC50: 16nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380782((6R)-6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d...)
IC50: 17nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380712(6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2...)
IC50: 18nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380712(6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2...)
BDBM380782((6R)-6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d...)
IC50: 980nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair