Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380695((R)-6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d]...)
BDBM380695((R)-6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d]...)
IC50: <11nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380693(6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2...)
IC50: 12nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380693(6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2...)
IC50: 13nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380695((R)-6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d]...)
IC50: 13nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380693(6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2...)
IC50: 17nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380695((R)-6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d]...)
BDBM380693(6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2...)
IC50: 1.45E+3nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair