Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
IC50: 38nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-8 using Ac-IETD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-3 using Ac-DEVD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-7 using Ac-DEVD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-6 using Ac-VEID-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair