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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 1.40nM
Assay Description:
Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 4nM
Assay Description:
Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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Ligand Info
CHEMBL
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Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
Copy SMILES
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Affinity Data
IC50: 21nM
Assay Description:
Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
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Target
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 23nM
Assay Description:
Inhibition of recombinant human p70S6K by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
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Target
Tyrosine-protein kinase Fgr
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 65nM
Assay Description:
Inhibition of recombinant human FGR by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
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Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 72nM
Assay Description:
Inhibition of recombinant human FLT4 by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 82nM
Assay Description:
Inhibition of recombinant human MEK2 by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 96nM
Assay Description:
Inhibition of recombinant human VGFR2 by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Tyrosine-protein kinase HCK
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 137nM
Assay Description:
Inhibition of recombinant human HCK by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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PubMed
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 142nM
Assay Description:
Inhibition of recombinant human MEK1 by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
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Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 311nM
Assay Description:
Inhibition of recombinant human RSK1 by radiometric assay in presence of [gamma-33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of CYP1A2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2C19 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by
ChEMBL
Ligand
BDBM50136226
(CHEMBL3753341)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI