Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 59 hits in this display
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)Ki: 4nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Ki: 4nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)Ki: 183nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Ki: 183nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)Ki: 1.83E+3nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)Ki: 3.37E+3nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Ki: 3.70E+3nM ΔG°: -28.8kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Ki: 1.03E+4nM ΔG°: -26.5kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Ki: 1.48E+4nM ΔG°: -25.6kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Ki: 1.89E+4nM ΔG°: -25.1kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Ki: 2.77E+4nM ΔG°: -24.2kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Ki: >1.00E+5nM ΔG°: >-21.2kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Beta-1 adrenergic receptor(Rattus norvegicus (Rat))The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Ki: >1.00E+5nM ΔG°: >-21.2kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Ki: 3.70E+6nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Ki: 1.03E+7nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
Beta-1 adrenergic receptor(Mus musculus)The Usa, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Beta-1 adrenergic receptor(Mus musculus)The Usa, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Ki: 1.89E+7nMAssay Description:β1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988...More data for this Ligand-Target Pair
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Ki: 2.77E+7nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
Beta-1 adrenergic receptor(Mus musculus)The Usa, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Ki: >1.00E+8nMAssay Description:β1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988...More data for this Ligand-Target Pair
Beta-1 adrenergic receptor(Mus musculus)The Usa, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Ki: >1.00E+8nMAssay Description:β1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988...More data for this Ligand-Target Pair
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
IC50: 6.09nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
IC50: 6.74nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
IC50: 184nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Kd: 2.75E+4nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
EC50: 18nMAssay Description:Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contractionMore data for this Ligand-Target Pair
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50221768(CHEMBL537445 | rac-(2S)-N-[(2R)-2-(3,5-dihydroxyph...)EC50: 8.20E+3nMAssay Description:Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contractionMore data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
EC50: 73nMAssay Description:Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...More data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Kd: 1.02E+4nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Kd: 347nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
EC50: 0.300nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...More data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
EC50: 4.70nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...More data for this Ligand-Target Pair
BDBM50213114((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Kd: 2.75E+4nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
BDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
BDBM50213103((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Kd: 1.02E+4nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
BDBM50213098((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Kd: 347nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
BDBM50213106((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Kd: 3.72E+3nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
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