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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetProtein kinase C theta type(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKA-theta (unknown origin) using Fam-labelled S6-derived peptide incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  150nMAssay Description:Inhibition of PKC-theta in PBMC isolated from human leukocyte reduction system white blood cells isolated assessed as reduction in anti-CD3/CD28-stim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  290nMAssay Description:Inhibition of PKC-theta in human mixed lymphocyte reaction assessed as reduction in anti-CD3/CD28-stimulated IL-2 expression measured for 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  330nMAssay Description:Inhibition of PKC-theta in PBMC isolated from human leukocyte whole blood assessed as reduction in anti-CD3/CD28-stimulated IL-2 expression measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Mus musculus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  590nMAssay Description:Inhibition of PKC-theta in mouse mixed lymphocyte reaction assessed as reduction in anti-CD3/CD28-stimulated IL-2 expression measured for 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of PKC-theta in human whole blood assessed as reduction in anti-CD3/CD28-stimulated IL-2 expression measured for 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Mus musculus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  4.31E+3nMAssay Description:Inhibition of PKC-theta in mouse whole blood assessed as reduction in anti-CD3/CD28-stimulated IL-2 expression measured for 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of PKA-delta (unknown origin) using Fam-labelled S6-derived peptide incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed