Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed