Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331803((S)-3-(4-fluorophenyl)-6-((4-(1,1,1-trifluoro-2-hy...)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of labeled MK-499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331803((S)-3-(4-fluorophenyl)-6-((4-(1,1,1-trifluoro-2-hy...)
Affinity DataIC50:  21nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331803((S)-3-(4-fluorophenyl)-6-((4-(1,1,1-trifluoro-2-hy...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant 5-lipoxygenase assessed as arachidonic acid oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331803((S)-3-(4-fluorophenyl)-6-((4-(1,1,1-trifluoro-2-hy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of 5-lipoxygenase activating proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331803((S)-3-(4-fluorophenyl)-6-((4-(1,1,1-trifluoro-2-hy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331803((S)-3-(4-fluorophenyl)-6-((4-(1,1,1-trifluoro-2-hy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed