Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetNeutrophil elastase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50502658(CHEMBL4557877)Copy SMILESCopy InChI

Affinity DataKi:  3.20nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-MCA as substrate by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMyeloblastin(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50502658(CHEMBL4557877)Copy SMILESCopy InChI

Affinity DataKi:  7nMAssay Description:Inhibition of purified human proteinase 3 using MeOSuc-AAPV-MCA as substrate by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50502658(CHEMBL4557877)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human alpha thrombin using Boc-VPR-MCA as substrate by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50502658(CHEMBL4557877)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Cathepsin G using Suc-AAPF-MCA as substrate by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTrypsin(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50502658(CHEMBL4557877)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human trypsin using Boc-VPR-MCA as substrate by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50502658(CHEMBL4557877)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris using NleTDY-pNA as substrate by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL

LigandBDBM50502658(CHEMBL4557877)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI