Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL

LigandBDBM50436055(CHEMBL2397076)Copy SMILESCopy InChI

Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL

LigandBDBM50436055(CHEMBL2397076)Copy SMILESCopy InChI

Affinity DataKd:  13nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI