Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetRenin-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50022862(Boc-Phe-Ala-Leu-Val-Ile-His-OMe | CHEMBL101874)Copy SMILESCopy InChI

Affinity DataIC50:  500nMAssay Description:Inhibitory activity against mouse reninMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50022862(Boc-Phe-Ala-Leu-Val-Ile-His-OMe | CHEMBL101874)Copy SMILESCopy InChI

Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against human reninMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Bos taurus)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50022862(Boc-Phe-Ala-Leu-Val-Ile-His-OMe | CHEMBL101874)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against bovine cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPepsin A(Porcine)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50022862(Boc-Phe-Ala-Leu-Val-Ile-His-OMe | CHEMBL101874)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against porcine pepsinMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI