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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Baculoviral IAP repeat-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
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Affinity Data
Ki: 188nM
Assay Description:
Competitive inhibition of human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Baculoviral IAP repeat-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
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Copy InChI
Affinity Data
Ki: 328nM
Assay Description:
Competitive inhibition of human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP [241-356]
(Homo sapiens (Human))
University of Michigan
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
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Affinity Data
Ki: 580nM ΔG°: -35.2kJ/mole
pH: 7.5 T: 2°C
Assay Description:
A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP [241-356]
(Homo sapiens (Human))
University of Michigan
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 580nM ΔG°: -35.2kJ/mole
pH: 7.5 T: 2°C
Assay Description:
Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.54E+3nM
Assay Description:
Competitive inhibition of human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Baculoviral IAP repeat-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 999nM
Assay Description:
Competitive inhibition of human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Baculoviral IAP repeat-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.19E+3nM
Assay Description:
Competitive inhibition of human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM13200
((2S,3S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.16E+4nM
Assay Description:
Competitive inhibition of human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI