Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetRenin(Homo sapiens (Human))
E. Merck Darmstadt

Curated by ChEMBL

LigandBDBM50010411(CHEMBL113209 | {3-[(3-{1-[(4-Amino-2-methyl-pyrimi...)Copy SMILESCopy InChI

Affinity DataIC50:  70nMAssay Description:In vitro for inhibitory activity against human reninMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Bos taurus)
E. Merck Darmstadt

Curated by ChEMBL

LigandBDBM50010411(CHEMBL113209 | {3-[(3-{1-[(4-Amino-2-methyl-pyrimi...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPepsin A(Porcine)
E. Merck Darmstadt

Curated by ChEMBL

LigandBDBM50010411(CHEMBL113209 | {3-[(3-{1-[(4-Amino-2-methyl-pyrimi...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against porcine Pepsin.More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI