Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL

LigandBDBM50008157(4-(1-{1-[1-Cyclohexylmethyl-3,3-difluoro-2-hydroxy...)Copy SMILESCopy InChI

Affinity DataIC50:  1.5nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL

LigandBDBM50008157(4-(1-{1-[1-Cyclohexylmethyl-3,3-difluoro-2-hydroxy...)Copy SMILESCopy InChI

Affinity DataIC50:  259nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI