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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM122509(US8729061, 39)
Affinity DataIC50:  0.558nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM122509(US8729061, 39)
Affinity DataIC50:  11.4nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetCathepsin K(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM122509(US8729061, 39)
Affinity DataIC50:  63.6nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetCathepsin B(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM122509(US8729061, 39)
Affinity DataIC50:  140nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent