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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM122520(US8729061, 50)
Affinity DataIC50:  2.76nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM122520(US8729061, 50)
Affinity DataIC50:  8.60nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin B(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM122520(US8729061, 50)
Affinity DataIC50:  68.8nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM122520(US8729061, 50)
Affinity DataIC50:  119nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent