Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 100 hits in this display   

TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant full length His-tagged NUAK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant His-tagged FLT3 cytoplasmic domain (564 to 958 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  21nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  76nMAssay Description:Inhibition of human recombinant His-tagged KIT cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  98nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  136nMAssay Description:Inhibition of human recombinant full length His-tagged PDK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  157nMAssay Description:Inhibition of human recombinant His-tagged NTRK3 cytoplasmic domain (510 to 825 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  163nMAssay Description:Inhibition of human recombinant full length His-tagged AURKB expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  167nMAssay Description:Inhibition of human full length wild type DYKDDDDK-tagged LRRK2 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  206nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha2/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  494nMAssay Description:Inhibition of human recombinant His-tagged NTRK1 cytoplasmic domain (441 to 796 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  591nMAssay Description:Inhibition of human recombinant His-tagged FGFR2 cytoplasmic domain (403 to 822 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  605nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  658nMAssay Description:Inhibition of human recombinant full length GST/His-tagged CDK5/P25 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  668nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged SRC cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  692nMAssay Description:Inhibition of human recombinant full length His-tagged RPS6KA3 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  793nMAssay Description:Inhibition of human recombinant full length His-tagged CDK7/cyclin H/MNAT1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  818nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged LCK cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant GST-tagged CLK2 catalytic domain (137 to 498 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human recombinant GST-tagged TEK cytoplasmic domain (817 to 1101 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human recombinant full length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of human recombinant GST-tagged JAK2 cytoplasmic domain (809 to 1153 +9 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of human recombinant GST-tagged INSR cytoplasmic domain (1011 to 1382 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human recombinant N-terminal His-tagged MET cytoplasmic domain (956 to 1390 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human recombinant GST-tagged MAP3K8 catalytic domain (30 to 397 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of human recombinant full length His-tagged BMX cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human recombinant His-tagged KDR cytoplasmic domain (789 to 1356 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human recombinant full length His-tagged CDK9/cyclin T1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of human recombinant full length GST-tagged MAPK1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged HCK cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of human recombinant full length His-tagged BTK cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of human recombinant full length GST-tagged BRAF expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of human recombinant His-tagged EPHA3 cytoplasmic domain (569 to 976 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged IGF1R cytoplasmic domain (960 to 1397 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of human recombinant GST-tagged EPHB2 cytoplasmic domain (616 to 884 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of human recombinant full length His-tagged CHEK2 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 26(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  2.22E+3nMAssay Description:Inhibition of human recombinant full length GST-tagged MST4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  2.99E+3nMAssay Description:Inhibition of human recombinant full length His-tagged GSK3B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTestis-specific serine/threonine-protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  3.12E+3nMAssay Description:Inhibition of human recombinant full length His-tagged STK22D expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human recombinant GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged GSK3A expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged ALK4 catalytic domain (150 to 505 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged DYRK1A expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged IKKepsilon expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAP2K6 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged PASK catalytic domain (879 to 1323 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PRKCQ expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged ROCK2 cytoplasmic domain (1 to 552 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged ZAP70 cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPKAPK5 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged CSNK2A1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged IKKbeta expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged TYK2 cytoplasmic domain (833 to 1187 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged TBK1 expressed in insect expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged IRAK4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged AKT2beta expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged CAMK4 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged CHEK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DAPK1 catalytic domain (1 to 363 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged ERBB2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-coupled receptor kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged GRK4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-coupled receptor kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged GRK6 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged JAK1 cytoplasmic domain (866 to 1154 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAP2K1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPK9 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPKAPK2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged MINK1 catalytic domain (1 to 320 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged PKN1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PLK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length PRKCZ expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PTK6 cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged SGK cytoplasmic domain (60 to 431 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length N-terminal GST-tagged SYK cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TAO2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged TAOK2 cytoplasmic domain (1 to 314 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PIK3 P110D/P85A expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged SPHK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PIM1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSRSF protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged SRPK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged RPS6KB1 cytoplasmic domain (1 to 421 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged ADRBK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged IRAK1 catalytic domain (194 to 712 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged PRKACA catalytic domain (1 to 351 residues) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPK8 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged NEK6 expressed in insect expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged AKT1alpha expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged AKT3gamma expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged CSNK1A1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged EPHA8 cytoplasmic domain (565 to 1005 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged ITK cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPK13 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PRKCI expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged ROCK1 cytoplasmic domain (1 to 535 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged NEK4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged MAPK14alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged PAK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged CDC42BPA catalytic domain (1 to 473 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 100 total ) | Next | Last >>