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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetHistone deacetylase 2(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044635(CHEMBL3309291)
Affinity DataIC50:  22nMAssay Description:Inhibition of human HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044635(CHEMBL3309291)
Affinity DataIC50:  37nMAssay Description:Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044635(CHEMBL3309291)
Affinity DataIC50:  49nMAssay Description:Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044635(CHEMBL3309291)
Affinity DataIC50:  65nMAssay Description:Inhibition of human HDAC3 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044635(CHEMBL3309291)
Affinity DataIC50:  66nMAssay Description:Inhibition of human HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044635(CHEMBL3309291)
Affinity DataIC50:  110nMAssay Description:Inhibition of human HDAC6 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044635(CHEMBL3309291)
Affinity DataIC50:  380nMAssay Description:Inhibition of human HDAC4 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed