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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
40
hits in this display
Target
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 21nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 21nM
Assay Description:
Inhibition of human carbonic anhydrase 5B
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 21nM
Assay Description:
Inhibition of full length human carbonic anhydrase 5b preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 25nM
Assay Description:
Inhibition of human carbonic anhydrase 14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 25nM
Assay Description:
Inhibition of full length human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 25nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Mus musculus (mouse))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 30nM
Assay Description:
Inhibition of full length mouse carbonic anhydrase 13 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Mus musculus (mouse))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 30nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Mus musculus (mouse))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 30nM
Assay Description:
Inhibition of mouse carbonic anhydrase 13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 32nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 32nM
Assay Description:
Inhibition of human carbonic anhydrase 5A
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 32nM
Assay Description:
Inhibition of full length human carbonic anhydrase 5a preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 35nM
Assay Description:
Inhibition of full length human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 35nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 35nM
Assay Description:
Inhibition of human carbonic anhydrase 7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 941nM
Assay Description:
Inhibition of full length human carbonic anhydrase 4 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 941nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 941nM
Assay Description:
Inhibition of human carbonic anhydrase 4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.88E+3nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.88E+3nM
Assay Description:
Inhibition of human recombinant transmembrane carbonic anhydrase 12-mediated CO2 hydration activity after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.88E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.88E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.14E+3nM
Assay Description:
Inhibition of full length human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.14E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.14E+3nM ΔG°: -32.0kJ/mole
pH: 7.5 T: 2°C
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.14E+3nM
Assay Description:
Inhibition of human recombinant cytosolic carbonic anhydrase 2-mediated CO2 hydration activity after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universidad Nacional De La Plata
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.45E+3nM
Assay Description:
Inhibition of human recombinant cytosolic carbonic anhydrase 1-mediated CO2 hydration activity after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universidad Nacional De La Plata
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.45E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universidad Nacional De La Plata
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.45E+3nM ΔG°: -30.9kJ/mole
pH: 7.5 T: 2°C
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universidad Nacional De La Plata
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.45E+3nM
Assay Description:
Inhibition of full length human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.58E+3nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.58E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 9 catalytic domain preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
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Affinity Data
Ki: 4.58E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MMDB
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Universite Montpellier Ii
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
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Affinity Data
Ki: 4.58E+3nM
Assay Description:
Inhibition of human recombinant transmembrane carbonic anhydrase 9-mediated CO2 hydration activity after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
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PDB
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In Depth
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Article
PubMed
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
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Affinity Data
Ki: 3.40E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 2 by 4-NPA hydrolysis assay
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
B.MOAD
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
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Affinity Data
Ki: 3.40E+5nM
Assay Description:
Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
PDB
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In Depth
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Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
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Affinity Data
Ki: 6.50E+5nM
Assay Description:
Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
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PC sid
PDB
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In Depth
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Article
PubMed
MMDB
PDB
3D Structure (crystal)
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Target
Carbonic anhydrase 3
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
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Affinity Data
Ki: 4.00E+6nM
Assay Description:
Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
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PC sid
PDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
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Copy InChI
Affinity Data
Kd: 2.50E+4nM
pH: 7.5
Assay Description:
Binding affinity to human carbonic anhydrase 2 in presence of 10 mM HEPES and 100 uM Na2SO4 at pH 7.5 by ThermoFluor method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by
ChEMBL
Ligand
BDBM13055
(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.50E+4nM
Assay Description:
Binding affinity to human CA2 by ThermoFluor assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI