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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 4.5nM
Assay Description:
Inhibition of wild type SHP2 (unknown origin) using DiFMUP as substrate preincubated for 30 mins followed by substrate addition and measured after 30...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Histone deacetylase
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 49nM
Assay Description:
Inhibition of recombinant human HDAC using fluorogenic substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 68nM
Assay Description:
Inhibition of recombinant his-tagged human HDAC1 using Ac-LeuGlyLys (Ac) AMC substrate preincubated for 5 mins followed by substrate addition and mea...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 166nM
Assay Description:
Inhibition of recombinant his-tagged human HDAC6 using Ac-LeuGlyLys (Ac) AMC substrate preincubated for 5 mins followed by substrate addition and mea...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 184nM
Assay Description:
Inhibition of full length recombinant his-tagged human HDAC2 using Ac-LeuGlyLys (Ac) AMC substrate preincubated for 5 mins followed by substrate addi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 381nM
Assay Description:
Inhibition of recombinant his-tagged human HDAC3 using Ac-LeuGlyLys (Ac) AMC substrate preincubated for 5 mins followed by substrate addition and mea...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 1.18E+3nM
Assay Description:
Inhibition of recombinant his-tagged human HDAC10 using Ac-ArgHisLys (Ac) Lys (Ac)-AMC substrate preincubated for 5 mins followed by substrate additi...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 7
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 2.68E+3nM
Assay Description:
Inhibition of recombinant human HDAC7 using Ac-LeuGlyLys (TFA)-AMC substrate preincubated for 5 mins followed by substrate addition and measured afte...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 2.90E+3nM
Assay Description:
Inhibition of recombinant his-tagged human HDAC8 using Boc-Lys (TFA)-AMC substrate preincubated for 5 mins followed by substrate addition and measure...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 5
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 3.83E+3nM
Assay Description:
Inhibition of recombinant N-terminal GST-tagged human HDAC5 expressed in HEK293 cells using Ac-LeuGlyLys (TFA)-AMC substrate preincubated for 5 mins ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 11
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50593161
(CHEMBL5198194)
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Affinity Data
IC50: 2.42E+4nM
Assay Description:
Inhibition of recombinant his-tagged human HDAC11 using Ac-LeuGlyLys (Ac) AMC substrate preincubated for 5 mins followed by substrate addition and me...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI