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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Signal transducer and activator of transcription 3
(Homo sapiens (Human))
University Of Pittsburgh
Curated by
ChEMBL
Ligand
BDBM196138
(US9211296, Table 7, Compd: 9)
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Affinity Data
IC50: 800nM
Assay Description:
Inhibition of IL-6-induced STAT3 phosphorylation in human Cal33 cells assessed as nuclear translocation by Western blot analysis
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Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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In Depth
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Article
PubMed
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Target
DNA polymerase
(Vaccinia virus (strain WR))
University of Pennsylvania
US Patent
Ligand
BDBM196138
(US9211296, Table 7, Compd: 9)
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Affinity Data
IC50: 5.30E+3nM
pH: 7.4 T: 2°C
Assay Description:
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
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In Depth
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US Patent
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Target
Signal transducer and activator of transcription 1-alpha/beta
(Homo sapiens (Human))
University Of Pittsburgh
Curated by
ChEMBL
Ligand
BDBM196138
(US9211296, Table 7, Compd: 9)
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Affinity Data
IC50: 5.90E+3nM
Assay Description:
Inhibition of IFNgamma-induced STAT1 phosphorylation in human Cal33 cells by Western blot analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
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