Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 9 hits in this display
BDBM372716(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
BDBM372715(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
IC50: 3.40nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM372712(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
IC50: 6.23nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM372715(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
BDBM372716(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
BDBM372712(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
BDBM372715(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
BDBM372712(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
IC50: 1.07E+5nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CatD is 0.05M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) i...More data for this Ligand-Target Pair
BDBM372716(((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-chloropyridin-2...)
IC50: 1.32E+5nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CatD is 0.05M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) i...More data for this Ligand-Target Pair