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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50:  15nMAssay Description:Inhibition of HDAC8 in human HeLa cells nuclear extract using Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50:  40nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed