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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229194
(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
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Affinity Data
IC50: 9nM
Assay Description:
Inhibition of HDAC1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229194
(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229194
(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of HDAC1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Kansai University
Curated by
ChEMBL
Ligand
BDBM50229194
(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
Inhibition of HDAC2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI