Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229194(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229194(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Affinity DataIC50:  12nMAssay Description:Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229194(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Affinity DataIC50:  40nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Kansai University

Curated by ChEMBL
LigandPNGBDBM50229194(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Affinity DataIC50:  470nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed