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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  0.0140nMAssay Description:Inhibitory concentration against recombinant human caspase-3 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  0.140nMAssay Description:Inhibitory concentration against recombinant human caspase-7 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  5.10nMAssay Description:Inhibitory concentration against recombinant human caspase-1 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  5.30nMAssay Description:Inhibitory concentration against recombinant human caspase-8 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50160976((3S)-3-(2-(5-tert-butyl-3-((4-methyl-1,2,5-oxadiaz...)
Affinity DataIC50:  5.29E+3nMAssay Description:Inhibition of human recombinant caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed