Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of human recombinant caspase 3 in NT2 by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed