Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetStromelysin-1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandBDBM13102(2-[butan-2-yl(4-methoxybenzene)sulfonamido]-N-hydr...)Copy SMILESCopy InChI

Affinity DataKi:  1.82E+3nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetBone morphogenetic protein 1(Homo sapiens (Human))
Fibrogen

Curated by ChEMBL

LigandBDBM13102(2-[butan-2-yl(4-methoxybenzene)sulfonamido]-N-hydr...)Copy SMILESCopy InChI

Affinity DataIC50:  1.12E+5nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI