Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
Plasmepsin II(Plasmodium falciparum)Saint Louis University
US Patent
BDBM234576(US9353089, Table 8, Compound 1)
Plasmepsin II(Plasmodium falciparum)Saint Louis University
US Patent
BDBM234576(US9353089, Table 8, Compound 1)
IC50: 45nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
Cathepsin E(Homo sapiens (Human))Saint Louis University
US Patent
BDBM234576(US9353089, Table 8, Compound 1)
Cathepsin D(Homo sapiens (Human))Saint Louis University
US Patent
BDBM234576(US9353089, Table 8, Compound 1)
IC50: 385nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair
BDBM234576(US9353089, Table 8, Compound 1)
IC50: 2.30E+3nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair