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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331557(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331557(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50:  16.6nMAssay Description:Inhibition of human cathepsin V by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331557(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50:  20.9nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331557(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50:  78nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as Lip10 accumulation by Western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331557(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50:  141nMAssay Description:Inhibition of human cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331557(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of human cathepsin B by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed