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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Cystic Fibrosis Foundation Therapeutics
US Patent
Ligand
BDBM301426
(4-amino-7-{1-[1-(3,4-difluorophenyl)-1H-1,2,3-tria...)
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Affinity Data
EC50: 41.2nM
Assay Description:
Fischer rat thyroid (FRT) cell lines stably expressing recombinant F508del V470 CFTR and halide-sensitive yellow fluorescent protein (Pedemonte et al...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Cystic Fibrosis Foundation Therapeutics
US Patent
Ligand
BDBM301426
(4-amino-7-{1-[1-(3,4-difluorophenyl)-1H-1,2,3-tria...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 28.4nM
Assay Description:
Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI