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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetChymotrypsinogen A(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  2.50E+3nMAssay Description:Concentration required to inhibit the enzyme chymotrypsinMore data for this Ligand-Target Pair
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TargetCathepsin S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+3nMAssay Description:Concentration required to inhibit the enzyme cathepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+4nMAssay Description:Concentration required to inhibit the enzyme pepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  16nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  22nMAssay Description:Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  3.00E+3nMAssay Description:Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  1.00E+5nMAssay Description:Concentration of the compound required to inhibit rat plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article