Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Massachusetts-Boston

Curated by ChEMBL

LigandBDBM50458951(CHEMBL4206171)Copy SMILESCopy InChI

Affinity DataIC50:  9.90nMAssay Description:Inhibition of human recombinant PLK1 by Z-Lyte assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Massachusetts-Boston

Curated by ChEMBL

LigandBDBM50458951(CHEMBL4206171)Copy SMILESCopy InChI

Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) incubated for 1 hr by AlphaScreen biotin-JQ1 competition assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain testis-specific protein(Homo sapiens (Human))
University Of Massachusetts-Boston

Curated by ChEMBL

LigandBDBM50458951(CHEMBL4206171)Copy SMILESCopy InChI

Affinity DataIC50:  8.47E+3nMAssay Description:Inhibition of BRDT-BD1 (unknown origin) incubated for 1 hr by AlphaScreen biotin-JQ1 competition assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI