Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329575((R)-2-amino-4-(4-(difluoromethoxy)-3-methylphenyl)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329575((R)-2-amino-4-(4-(difluoromethoxy)-3-methylphenyl)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329575((R)-2-amino-4-(4-(difluoromethoxy)-3-methylphenyl)...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329575((R)-2-amino-4-(4-(difluoromethoxy)-3-methylphenyl)...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329575((R)-2-amino-4-(4-(difluoromethoxy)-3-methylphenyl)...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of renin by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed