Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
52
hits in this display
Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
University Of Catania
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membranes by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Liver carboxylesterase 1
(Homo sapiens (Human))
Eisai
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.63E+5nM
Assay Description:
Inhibition of human CES1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase
(Homo sapiens (Human))
Hacettepe University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.64E+5nM
Assay Description:
Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 2B7
(Homo sapiens (Human))
The University Of British Columbia
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+6nM
Assay Description:
Inhibition of AZT glucuronidation by human recombinant UGT2B7
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cocaine esterase
(Homo sapiens (Human))
Eisai
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.90E+6nM
Assay Description:
Inhibition of human CES2
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2A6
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.15E+6nM
Assay Description:
Mechanism based inhibition of human cytochrome P450 2A6 measured by coumarin 7-hydroxylation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Leukotriene A-4 hydrolase
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50009834
(2-Propylvaleric acid sodium salt | CHEMBL433 | Dep...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human LTA4H Epoxide Hydrolase expressed in Escherichia coli BL21 (DE3) pLysS preincubated for 10 mins followed by addition ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Leukotriene A-4 hydrolase
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50009834
(2-Propylvaleric acid sodium salt | CHEMBL433 | Dep...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human LTA4H aminopeptidase activity expressed in Escherichia coli BL21 (DE3) pLysS assessed as formation of p-NA from Ala-p...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.90E+4nM
Assay Description:
Inhibition of human recombinant HDAC1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+4nM
Assay Description:
Inhibition of HADC1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+4nM
Assay Description:
Inhibition of human recombinant HDAC1 using fluorogenic substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member A1
(Homo sapiens (Human))
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.01E+4nM
Assay Description:
Inhibition of AK1A1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member A1
(Rattus norvegicus)
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.01E+4nM
Assay Description:
Inhibition of rat kidney aldehyde reductase at 0.1 mM after 20 mins by spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member A1
(Rattus norvegicus)
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.61E+4nM
Assay Description:
Inhibition of Fischer-344 rat kidney AK1A1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1
(Rattus norvegicus)
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.61E+4nM
Assay Description:
Inhibition of Fischer-344 rat kidney ALR1 using D-glucuronate as substrate by spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B7
(Rattus norvegicus)
Slovak Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.61E+4nM
Assay Description:
Inhibition of Wistar rat kidney aldehyde reductase using D-glucuronate as substrate by spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1
(Rattus norvegicus)
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.61E+4nM
Assay Description:
Inhibition of Fischer-344 rat kidney ALR1 using D,L-glyceraldehyde as substrate by spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1
(Rattus norvegicus)
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.61E+4nM
Assay Description:
Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1
(Rattus norvegicus)
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.61E+4nM
Assay Description:
Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1 [K65Q]
(Bos taurus (Cattle))
Quaid-I-Azam University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.74E+4nM
Assay Description:
Inhibition of ALR1 in calf kidney using sodium D-glucoronate as substrate treated with compound for 10 mins prior to substrate addition by UV spectro...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member A1
(Bos taurus (Cattle))
Comsats Institute of Information Technology
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.74E+4nM
pH: 6.2
Assay Description:
The assay results were obtained at 340 nm and ALR1 inhibitory activity was measured with the absorbance change at this respective wavelength. Each we...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.20E+4nM
Assay Description:
Inhibition of human recombinant HDAC2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.42E+4nM
Assay Description:
Inhibition of human full-length recombinant HDAC1 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member A1
(Sus scrofa)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50009834
(2-Propylvaleric acid sodium salt | CHEMBL433 | Dep...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.90E+4nM
Assay Description:
Selectivity ratio measured as the IC50 ratio of aldehyde/aldose reductase values
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NAD-dependent protein deacylase sirtuin-5, mitochondrial
(Homo sapiens (Human))
Technical University Of Denmark
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of SIRT5
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.03E+5nM
Assay Description:
Inhibition of human full-length recombinant HDAC2 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.03E+5nM
Assay Description:
Inhibition of human recombinant HDAC8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2b
(Zea mays)
Sapienza University Of Rome
Curated by
ChEMBL
Ligand
BDBM50009834
(2-Propylvaleric acid sodium salt | CHEMBL433 | Dep...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.28E+5nM
Assay Description:
Concentration required for inhibition of histone deacetylase HD2 in vitro.
Checked by Author
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2b
(Zea mays)
Sapienza University Of Rome
Curated by
ChEMBL
Ligand
BDBM50009834
(2-Propylvaleric acid sodium salt | CHEMBL433 | Dep...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.28E+5nM
Assay Description:
Inhibitory concentration against maize histone deacetylase 2
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Minia University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.35E+5nM
Assay Description:
Inhibition of human full-length recombinant HDAC3 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Minia University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.61E+5nM
Assay Description:
Inhibition of human recombinant HDAC3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.84E+5nM
Assay Description:
Inhibition of human full-length recombinant C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells preincubated for 5 mins fo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Minia University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.15E+5nM
Assay Description:
Inhibition of human full-length recombinant HDAC6 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1
(Rattus norvegicus)
Aristotle University Of Thessaloniki
Curated by
ChEMBL
Ligand
BDBM50009834
(2-Propylvaleric acid sodium salt | CHEMBL433 | Dep...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.80E+5nM
Assay Description:
Inhibitory activity measured against rat lens aldose reductase using 3-pyridinecarboxaldehyde as substrate
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+5nM
Assay Description:
Inhibition of HDAC1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+5nM
Assay Description:
Inhibition of HDAC2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Minia University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+5nM
Assay Description:
Inhibition of HDAC3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase
(Homo sapiens (Human))
Hacettepe University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.95E+5nM
Assay Description:
Inhibition of human HDAC in HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Rattus norvegicus)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 5
(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+6nM
Assay Description:
Inhibition of HDAC5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Minia University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+6nM
Assay Description:
Inhibition of HDAC6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histone deacetylase 4
(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+6nM
Assay Description:
Inhibition of HDAC4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Tissue factor
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+6nM
Assay Description:
Inhibition of LPS-induced tissue factor activity in HUVEC preincubated for 4 hrs assessed after 4 hrs of LPS challenge by one stage clotting assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 7
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+6nM
Assay Description:
Inhibition of human recombinant HDAC7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 5
(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+6nM
Assay Description:
Inhibition of human recombinant HDAC5
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 4
(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+6nM
Assay Description:
Inhibition of human recombinant HDAC4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tissue factor
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+6nM
Assay Description:
Inhibition of TNF-alpha-induced tissue factor activity in HUVEC preincubated for 4 hrs assessed after 4 hrs of TNFalpha challenge by one stage clotti...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 9
(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+6nM
Assay Description:
Inhibition of human recombinant HDAC9
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Minia University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+6nM
Assay Description:
Inhibition of human recombinant HDAC6
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase
(Homo sapiens (Human))
Hacettepe University
Curated by
ChEMBL
Ligand
BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.24E+6nM
Assay Description:
Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Displayed 1 to 50 (of 52 total ) |
Next
|
Last
>>