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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50569639
(CHEMBL4858081)
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Affinity Data
IC50: 250nM
Assay Description:
Inhibition of recombinant human C-terminal FLAG-tagged HDAC1 expressed in human HEK293F cells using Fluor-de-lys substrate as substrate incubated for...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 3
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50569639
(CHEMBL4858081)
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Affinity Data
IC50: 360nM
Assay Description:
Inhibition of recombinant human FLAG-tagged HDAC3 expressed in human HEK293F cells co-expressing His6-tagged SMRT (1 to 899 residues) using Fluor-de-...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50569639
(CHEMBL4858081)
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Affinity Data
IC50: 500nM
Assay Description:
Inhibition of recombinant human C-terminal FLAG-tagged HDAC2 expressed in human HEK293F cells using Fluor-de-lys substrate as substrate incubated for...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 1/2/3/8
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50569639
(CHEMBL4858081)
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Affinity Data
IC50: 860nM
Assay Description:
Inhibition of class 1 HDAC in human Jurkat 2C4 model of HIV latency assessed as reactivation of HIV latency incubated for 18 to 24 hrs in presence of...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50569639
(CHEMBL4858081)
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Affinity Data
IC50: 1.60E+3nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes assessed as reduction in 4'-hydroxy diclofenac level using diclofenac as substrate incubated for 10 mi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Nuclear receptor subfamily 1 group I member 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50569639
(CHEMBL4858081)
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Affinity Data
EC50: 2.50E+3nM
Assay Description:
Activation of PXR (unknown origin) expressed in human DPX2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as induction...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI