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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152527((1-benzylcyclobutyl)methyl(S)-1,2-dioxo-1-((R)-1-p...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152527((1-benzylcyclobutyl)methyl(S)-1,2-dioxo-1-((R)-1-p...)
Affinity DataIC50:  8.51nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152527((1-benzylcyclobutyl)methyl(S)-1,2-dioxo-1-((R)-1-p...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 10 uM Cbz-Val-Val-Arg-AMC binding to human cathepsin S in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152527((1-benzylcyclobutyl)methyl(S)-1,2-dioxo-1-((R)-1-p...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 5 uM Cbz-Phe-Arg-AMC human cathepsin L in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152527((1-benzylcyclobutyl)methyl(S)-1,2-dioxo-1-((R)-1-p...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin B in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152527((1-benzylcyclobutyl)methyl(S)-1,2-dioxo-1-((R)-1-p...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of 50 uM L-Arg-beta-naphthalamide binding to human cathepsin H in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed