Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL

LigandBDBM50458772(CHEMBL4211663)Copy SMILESCopy InChI

Affinity DataIC50:  200nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBone morphogenetic protein 1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL

LigandBDBM50458772(CHEMBL4211663)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI