Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)
Affinity DataIC50:  600nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212247(CHEMBL3982065)
Affinity DataIC50:  710nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)
Affinity DataIC50:  9.80E+4nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50:  5.30E+5nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50:  5.80E+5nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed