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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Department Of Chemistry And Applied Biosciences
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
Ki: 1.17E+4nM
Assay Description:
Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2C8
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 2.20E+3nM
Assay Description:
Inhibition of CYP2C8 in human liver microsomes using amodiaquin as substrate preincubated for 10 mins followed by NADPH addition measured after 10 mi...
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 6.80E+3nM
Assay Description:
Inhibition of recombinant human CYP2C9 expressed in baculosomes using Vivid OOMR substrate red measured every 30 sec for 30 mins by fluorescence assa...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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CHEMBL
KEGG
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 8.10E+3nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate preincubated for 10 mins followed by NADPH addition measured after...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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DrugBank
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Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 8.10E+3nM
Assay Description:
Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 10 mins followed by NADPH addition measured after 20 min...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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CHEMBL
KEGG
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 8.10E+3nM
Assay Description:
Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate preincubated for 10 mins followed by NADPH addition measured after 10 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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antibodypedia
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CHEMBL
KEGG
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 8.70E+3nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMCC substrate blue measured every 30 sec for 30 mins by fluorescence as...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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B.MOAD
DrugBank
antibodypedia
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CHEMBL
KEGG
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Article
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 8.70E+3nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by NADPH addition measured after 7 min...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
KEGG
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 1.05E+4nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMR substrate red measured every 30 sec for 30 mins by fluorescence assa...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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B.MOAD
DrugBank
antibodypedia
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CHEMBL
KEGG
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PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 1.16E+4nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid DBOMF substrate green measured every 30 sec for 30 mins by fluorescence a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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CHEMBL
KEGG
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PubMed
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 1.25E+4nM
Assay Description:
Binding affinity towards human Melanocortin 1 receptor (hMC1R)
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 2.73E+4nM
Assay Description:
Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 10 mins followed by NADPH addition measured after 10 mi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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CHEMBL
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PubMed
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 4.27E+4nM
Assay Description:
Binding affinity towards human Melanocortin 1 receptor (hMC1R)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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Ligand Info
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CHEMBL
KEGG
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In Depth
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PubMed
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Target
Cytochrome P450 2A6
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.90E+4nM
Assay Description:
Inhibition of CYP2A6 in human liver microsomes using Coumarin as substrate preincubated for 10 mins followed by NADPH addition measured after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
KEGG
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.45E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition measured after...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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CHEMBL
KEGG
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Target
Cytochrome P450 2E1
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317426
(8-Gingerol | CHEMBL1095671)
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Affinity Data
IC50: 9.32E+4nM
Assay Description:
Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 10 mins followed by NADPH addition measured after 20...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI