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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Histone deacetylase 8
(Homo sapiens (Human))
Fudan University
Curated by
ChEMBL
Ligand
BDBM50515973
(CHEMBL4524784)
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Affinity Data
IC50: 255nM
Assay Description:
Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubate...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 1
(Homo sapiens (Human))
Fudan University
Curated by
ChEMBL
Ligand
BDBM50515973
(CHEMBL4524784)
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Copy InChI
Affinity Data
IC50: 385nM
Assay Description:
Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Fudan University
Curated by
ChEMBL
Ligand
BDBM50515973
(CHEMBL4524784)
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Affinity Data
IC50: 1.82E+3nM
Assay Description:
Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
Fudan University
Curated by
ChEMBL
Ligand
BDBM50515973
(CHEMBL4524784)
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Affinity Data
IC50: 2.30E+3nM
Assay Description:
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Fudan University
Curated by
ChEMBL
Ligand
BDBM50515973
(CHEMBL4524784)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of recombinant human HDAC6 using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI