Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL

LigandBDBM50285502(CHEMBL77583 | N-{[(2,6-isopropylphenyl)amino]carbo...)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+3nMAssay Description:Compound at 5 microM concentration was tested in vitro for inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in intestinal microsomes of cho...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/TrEMBL
DrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails Article
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TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL

LigandBDBM50285502(CHEMBL77583 | N-{[(2,6-isopropylphenyl)amino]carbo...)Copy SMILESCopy InChI

Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in liver microsomes of cholesterol fed ratsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails Article
Copy BDB DOI