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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
Ki: 0.450nM
Assay Description:
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C epsilon
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
Ki: 0.800nM
Assay Description:
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C delta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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ChEBI
CHEMBL
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Article
PubMed
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Target
Protein kinase C beta type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
Ki: 1.80nM
Assay Description:
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
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Target
Protein kinase C alpha type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Copy InChI
Affinity Data
Ki: 2.5nM
Assay Description:
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C alpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Protein kinase C gamma type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
Ki: 4.90nM
Assay Description:
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C gamma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C alpha type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.40nM
Assay Description:
Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Luciferin 4-monooxygenase
(Photinus pyralis)
Indian Institute Of Technology Madras
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
EC50: 10nM
Assay Description:
Activation of firefly luciferase activity expressed in HEK293T cells after 6 hrs by luminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
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Ligand Info
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ChEBI
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
EC50: 5.17E+3nM
Assay Description:
Binding affinity to GST-tagged PKCdelta expressed in Escherichia coli BL21(DE3) by fluorescence quenching
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Copy InChI
Affinity Data
EC50: 5.56E+3nM
Assay Description:
Binding affinity to GST-tagged PKCepsilon expressed in Escherichia coli BL21(DE3) by fluorescence quenching
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Homo sapiens (Human))
University Of Houston
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
EC50: 3.19E+3nM
Assay Description:
Binding affinity to GST-tagged PKCtheta expressed in Escherichia coli BL21(DE3) by fluorescence quenching
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ras guanyl-releasing protein 3
(Homo sapiens (Human))
Seoul National University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
EC50: 82nM
Assay Description:
Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells after 30 mins by immunoblot method
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
KEGG
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C delta type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Copy SMILES
Copy InChI
Affinity Data
EC50: 290nM
Assay Description:
Activation of PKCdelta (unknown origin) expressed in HEK293 cells harboring GFP-tagged RasGRP3 assessed as phosphorylation at ser299 residues after 3...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139
(Homo sapiens (Human))
Kaohsiung Medical University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
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Affinity Data
EC50: 9.5nM
Assay Description:
Activation of PKC in human platelet assessed as induction of platelet aggregation measured within 15 mins by tribidimetric method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C alpha type
(Homo sapiens (Human))
Georgetotwn University
Curated by
ChEMBL
Ligand
BDBM50099066
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.70E+6nM
Assay Description:
Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI